(i) total arthritis index and hind paw edema ↓(ii) inflammatory cell infiltration ↓(iii) cartilage and subchondral bone degradation ↓(iv) serum IL-6 and NO metabolites ↓(v) NF-κB activation ↓(vi) synovial hyperproliferation ↓(vii) clonal expansion of T cells ↓. Here, IL6 is linked to Arthritis.