In addition, a current pan-cancer analysis revealed that PINK1 mRNA expression was reduced across multiple cancer types compared to normal tissues, including brain, breast, colorectal, esophageal, head and neck, liver, and ovarian cancers, as well as leukemia and melanoma, while elevated expression was observed in diffuse large B-cell lymphoma [30]. This evidence concerns the gene PINK1 and diffuse large B-cell lymphoma.