SYK and tauopathy: To explore the role of Clec7a in the PS19 mouse model of tauopathy, we assessed the expression of Clec7a and phosphorylated SYK (p-SYK) in the ventral hippocampus (vHPC) (Figure 2A–D), dorsal hippocampus (dHPC) (Figure S1D–G), and cortex (Figure S2A–D) of PS19 mice and their wild-type (WT) littermates at 3, 6, 9, and 12 months.