Patients suffering from hypertension showed higher percentages of Tregs expressing PD-1 on the surface than the HC group: Foxp3+Helios-CD279+ Tregs (Figure 2H), Foxp3+Helios+CD279+ Tregs (Figure 2I) and Foxp3-Helios+CD279+ Tregs (Figure 2J). The gene discussed is FOXP3; the disease is Hypertension.