In addition, it was also found in experiments on animal models of asthma that aerobic training reduced inflammatory cell infiltration, decreased EOS migration and nuclear factor‐κB (NF‐κB) expression by inducing an increase in the expression of anti‐inflammatory cytokines, while decreasing the expression of Th2 cytokine‐β, transforming growth factor‐β (TGF‐β), leukocyte chemokines (eotaxin and RANTES), vascular endothelial growth factor (VEGF), and adhesion molecules (ICAM‐1, VCAM‐1) pro‐inflammatory factors expression and decreased AHR and inflammatory factor levels in asthmatic mice [38]. This evidence concerns the gene ICAM1 and asthma.