TREM2 and neoplasm: found that in an intracranial glioma model, stereotactic injection of luciferase-labeled GL261 cells (GL261-luc) into the brains of mice revealed that Trem2−/− mice, although showing no significant difference in survival rates, exhibited higher tumor burden and faster tumor growth, suggesting that TREM2 may inhibit the growth of intracranial gliomas.