While immunotherapy is known for exacerbating or unmasking underlying autoimmune conditions, immunotherapy-related sialadenitis can present as a distinct entity from Sjögren's syndrome, with no evidence of characteristic anti-Sjögren's syndrome-related antigen A (SS-A)/Sjögren's syndrome-related antigen B (SS-B) or antinuclear antibodies and with distinct salivary gland pathology on biopsy [5]. This evidence concerns the gene SSB and sialadenitis.