Genome-wide association study (GWAS) data on exposures, which included hyperthyroidism, hypothyroidism, and thyroid-stimulating hormone (TSH), were extracted from the MRC Integrative Epidemiology Unit (MRC-IEU) (https://gwas.mrcieu.ac.uk/), and GWAS data for outcomes, including hepatic fibrosis/cirrhosis and chitinase-3-like protein 1 (CHI3L1), were obtained from the FinnGen consortium (https://www.finngen.fi/fi). The gene discussed is CHI3L1; the disease is hyperthyroidism.