The latter study, along with another investigation assessing SANG’s efficacy in ameliorating fatty liver disease in mouse hepatocytes have reported that SANG could enhance the expression of Nrf2 and peroxisome proliferator-activated receptor γ (PPAR-γ) which improves the antioxidant activity (Zheng et al., 2022; Tian et al., 2021). This evidence concerns the gene GNAS-AS1 and fatty liver disease.