BRAF and adenocarcinoma: Primary BRAF-mutated patients had more elderly (median age: 67 versus 61, p=0.015), males (53.4% vs 26.7%, p=0.056), former/current smokers (36.5% vs 6.7%, p=0.033), non-adenocarcinoma (11.4% vs 0%, P=0.351) patients than the acquired BRAF-mutated cohort.