Choudhury found that SIRT7 regulates glutamine metabolism through the TGF-β/SIRT7/FOXO4 axis, promotes the deacetylation of FOXO4, thereby inhibiting the expression of GLS1, and thus controls the progression of pulmonary fibrosis (Choudhury et al., 2020, p. 1). Here, TGFB1 is linked to pulmonary fibrosis.