SIRT6 and pulmonary fibrosis: It has been confirmed that SIRT1, SIRT2, SIRT3, SIRT6 and SIRT7 significantly inhibit the development of lung fibrosis (Bindu et al., 2017; Wyman et al., 2017; Chu et al., 2018; Zhang et al., 2019b; Gong et al., 2021).