When pulmonary fibrosis develops, EMT is thought to be a reversible process in which epithelial cells eventually lose the epithelial cell adhesion protein E-cadherin (E-cad) and gain mesenchymal traits including the mesenchymal marker α-smooth muscle actin (α-SMA) (Bartis et al., 2014; Qu et al., 2019). The gene discussed is CDH1; the disease is pulmonary fibrosis.