Furthermore, we also investigated a selection of prognostic markers in ccRCC including CA9, VEGFA, and FN1, which highlighted a model‐specific expression pattern with an upregulation of CA9 and VEGFA within the in vivo models and an upregulation of FN1 within the in vitro model (Fig. 2D). This evidence concerns the gene CA9 and nonpapillary renal cell carcinoma.