Activation of cGAS‐STING in tumour cells or antigen‐presenting cells (APCs) within the tumour microenvironment (TME) has been shown to promote phagocytosis of tumour antigens, enhance antigen presentation, induce the release of type I interferons (IFNs) and facilitate T cell infiltration, thereby reversing immunosuppressive conditions within the TME (Samson and Ablasser 2022; Low et al. The gene discussed is STING1; the disease is neoplasm.