First, while interferon‐gamma (IFN‐γ) has been identified as crucial for OMV‐mediated tumour eradication, its activity alone cannot fully explain the potent anticancer performance of OMVs since IFN‐γ can also promote tumour immune evasion and progression through the regulation of immunosuppressive factors (Mojic et al. This evidence concerns the gene IFNG and neoplasm.