The hyperlipidaemia in the E3L.CETP mice was manifested by an increased plasma level of TG (2.20 vs 1.00 mmol/L, Fig. S1D) and non-HDL cholesterol (0.8 vs 0.17 mmol/L, Fig. S1E), as well as a decreased level of HDL cholesterol (0.15 vs 0.80 mmol/L, Fig. S1F) resulting in a slightly increased level of total cholesterol (2.50 vs 2.00 mmol/L, Fig. S1C) in comparison to the C57BL/6J mice. The gene discussed is CETP; the disease is hyperlipidemia.