The secreted anti-tumor immune effector molecules interferon-gamma (IFN-γ) and granzyme B increased in the media from cultures including active T cells, with a pronounced boost using the strong activation protocol, and even higher for Granzyme B in PDS co-cultures, agreeing with the phenotypes observed by flow cytometry (Fig. 3b, c). The gene discussed is IFNG; the disease is neoplasm.