Another commonly used model is the rd1 mouse, carrying a mutation in the Pde6b gene, is a commonly used model for retinitis pigmentosa (RP) due to its rapid and early photoreceptor degeneration, making it an efficient system for studying therapeutic interventions (Barber et al., 2013; Barnea-Cramer et al., 2016, 2020; MacLaren et al., 2006; Pearson et al., 2016; Ribeiro et al., 2021). The gene discussed is PDE6B; the disease is retinitis pigmentosa.