We also observed that NDUFB11 and COQ2 showed very high dependency scores in human DNMT3A-mutant AML cell lines among the 37 myeloid cell lines with available data (Extended Data Fig. 4a), and SLC25A1 was also depleted in all three DNMT3A-mutant lines, albeit more modestly. This evidence concerns the gene DNMT3A and acute myeloid leukemia.