5-FU-miR-15a was also shown to significantly inhibit the expression of Yap1, Bcl2, interleukin-6 (IL-6), and Mmp9 alone and during treatment with transforming growth factor β1 (TGF-β1) in murine and human pancreatic stellate cells, suggesting reduced proliferation and migration of pancreatic stellate and cancer cells. Here, IL6 is linked to cancer.