A study has highlighted that the diallyl disulfide, an organosulfur compound in garlic, induces histone H4 and/or histone H3 acetylation in the CDKN1A promoter region and results in elevated expression of CDKN1A mRNA and p21WAF1 in Caco-1 and HT-29 cancer cell lines, thus preventing cell proliferation and also causing cell cycle arrest [59]. The gene discussed is CDKN1A; the disease is cancer.