In GSE1919, CXCL10 and IL15 were significantly highly expressed, and FOXO3 was significantly less expressed in the RA group than the HC group (Fig 9C), and the AUC values of CXCL10, IL15, and FOXO3 in the ROC curves were 0.95, 0.98, and 0.78 (Fig 9D). This evidence concerns the gene IL15 and rheumatoid arthritis.