Case–control studies have shown that postmenopausal women with PCOS have higher androgen (testosterone, free androgen index, 17 hydroxyprogesterone, androstenedione and DHEAS) and lower sex hormone-binding globulin levels than women without PCOS (Markopoulos et al. 2011, Schmidt et al. 2011). Here, SULT2A1 is linked to polycystic ovary syndrome.