The mentioned association study in 58,998 CRC patients and 71,171 controls found no association with CRC for the most commonly reported PVs in NTHL1-associated polyposis: c.268C>T, p.Gln90Ter (rs150766139) and c.859C>T, p.Gln287Ter (rs146347092) [86]. Here, NTHL1 is linked to polyposis.