Notably, the analysis results suggested the activation of MYC and the ETS family transcription factors ETS1, ELF2, ELF5, ELK1, GABPA, GABPB2, NRF2, CETS1P54, DIDO1, and EPC1 in CNS tumors with FOXR2 overexpression, as suggested by previous studies in various tumor types.2,39,40. Here, ETS1 is linked to central nervous system neoplasm.