FOXR2 and embryonal neoplasm: The findings of our blinded imaging review were consistent with the reported imaging characteristics of FOXR2-activated CNS NB.42 The distinctive imaging features can help differentiate CNS NB from other embryonal tumors, such as embryonal tumors with multilayered rosettes, which have prominent intra-tumoral veins and hypo-enhancement.43 On follow-up imaging, pseudoprogression was only observed in a subset of pontine DMGs and was notably absent in thalamic, spinal, and hemispheric HGGs.