FOXR2 and neuroblastoma: Chromosome arm 1q gain (1q+), a characteristic molecular alteration of CNS NB-FOXR2, was seen in 70.6% (12/17) of HGGs with FOXR2 overexpression tested, demonstrating that the combination of 1q+ and FOXR2 overexpression is not specific to CNS NB-FOXR2.