4CMenB vaccinated animals had a statistically lower score in a day 6 post-challenge vaginal lavage component that was highly correlated with a large number of chemokines and pro-inflammatory cytokines (Fig. S18, bottom), whereas protected 4CMenB immunized animals had a lower average score compared with not protected animals in a pre-infection lavage component that was positively correlated with certain chemokines (fractalkine and KC) and negatively correlated with others (TARC, 6Ckine/Exodus 2, and IP-10) (Fig. S18, top). This evidence concerns the gene CXCL10 and infection.