Conversely, elevated expression of NLRP1 was observed in Head and Neck Squamous Cell Carcinoma (HNSC), Kidney Renal Clear Cell Carcinoma (KIRC), Liver Hepatocellular Carcinoma (LIHC) (p‐value < 0.001), as well as Cholangio Carcinoma (CHOL) (p‐value < 0.01) and Esophageal carcinoma (ESCA) (p‐value < 0.05) when compared to normal tissues (Figure 2A, Table 1). The gene discussed is NLRP1; the disease is head and neck squamous cell carcinoma.