Additionally, a negative association was identified between NLRP1 transcriptional level and CAF in specific subgroups, such as HPV‐negative HNSC, BRCA basal cell carcinoma, BRCA HER2 positive, BRCA‐lumA, BRCA‐lumB, and SKCM metastasis based on the EPIC algorithm. Here, NLRP1 is linked to basal cell carcinoma.