Findings from the starBase database further validated the downregulated expression of NLRP1 in tumor tissues of BLCA, BRCA, COAD, KICH, LUAD, LUSC, PRAD, and UCEC, while KIRC, LIHC, CHOL, and HNSC exhibited higher expression levels relative to normal tissues, with FDR < 0.05 (Figure 2B, Table 1). Here, NLRP1 is linked to neoplasm.