Alternatively, the starBase database highlighted the association between NLRP1 downregulation and diminished OS in PAAD (p = 0.0032, HR = 0.53), SKCM (p = 0.0057, HR = 0.68), ACC (p = 0.024, HR = 0.41), LUAD (p = 0.0056, HR = 0.66), and HNSC (p = 0.025, HR = 0.73), while NLRP1 upregulation was related to adverse OS in KIRC (p = 0.043, HR = 1.37) and DLBC (p = 0.024, HR = 8.12) (Figure 5B, Table 2). Here, NLRP1 is linked to adrenal cortex carcinoma.