Consequently, upon implementing the purity‐adjusted EPIC algorithm, the analysis revealed a negative correlation between NLRP1 expression and CAFs in ACC, BRCA, CESC, COAD, ESCA, Glioblastoma Multiforme (GBM), HNSC, KICH, KIRC, KIRP, LGG, LIHC, LUAD, LUSC, MESO, OV, PAAD, PCPG, PRAD, READ, SKCM, STAD, TGCT, Thyroid Carcinoma (THCA), Thymoma (THYM), and UCEC. The gene discussed is NLRP1; the disease is thyroid gland carcinoma.