The GEPIA2 database analysis revealed downregulation of the NLRP1 gene in tumor tissues of BLCA, BRCA, Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (CESC), COAD, Lymphoid Neoplasm Diffuse Large B‐cell Lymphoma (DLBC), KICH, LUAD, LUSC, Ovarian Serous Cystadenocarcinoma (OV), PRAD, READ, Skin Cutaneous Melanoma (SKCM), Testicular Germ Cell Tumors (TGCT), UCEC, and Uterine Carcinosarcoma (UCS). This evidence concerns the gene NLRP1 and bladder transitional cell carcinoma.