TNF and cancer: A total of 91 KEGG pathway enrichment items were identified, primarily involving the signaling pathways related to advanced glycation end products (AGE) and their receptor (RAGE) signalling pathway in diabetic complications, fluid shear stress, and atherosclerosis, lipid and atherosclerosis, pathways in cancer, TNF signaling pathway, hypoxia-inducible factor 1 (HIF-1) signaling pathway, mitogen-activated protein kinase (MAPK) signaling pathway, and interleukin-17 (IL-17) signaling pathway.