C1QA and bacterial infectious disease: The pathway analysis based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) databases showed that the specifically enriched plasma proteins of the septic mice by P12 (vs. the bare GNP) were strongly associated with the complement and coagulation cascades (e.g., complement 1qα, C1qα), chemokine signaling pathways, bacterial infections, cytokine-cytokine receptor interaction and endocytosis (Fig. 6F, Fig. S13).