As expected, B. pseudolongum administration significantly declined the escape latency (Figure 4B), the latency to the target hole (Figure 4C), and the number of approaches to the target hole (Figure S6D), as well as reduced Aβ accumulation and increased Iba‐1+ cell surrounds per plaque in AD mice (Figure 4D–F and Figure S6F–H). Here, AIF1 is linked to Alzheimer disease.