GPT and Cirrhosis: These effects were associated with an improvement of fibrosis and of circulating ALT and DPP4 (Supplementary Figure 3C), while they preceded appreciable lowering of steatosis (Supplementary Figure 3B) and the complete offset of hepatic inflammation (Supplementary Figure 3D), indicating that KD has an early and effective impact on the pro-fibrogenic mechanisms involved in MASH evolution to fibrosis/cirrhosis.