However, Tex in human cancers frequently expressed additional cell surface receptors (CD27, CXCR6, LAYN, NKG7, TNFRSF1B, TNFRSF9, TNFRSF18), transcription factors and nuclear proteins (CCND2, RBPJ, ZBED2, ZNF683), as well as chemokines, cytokines, and granzymes (CCL3, CSF1, CXCL13, IFNG, FAM3C, GZMA, GZMB, PRF1). The gene discussed is CD27; the disease is cancer.