However, Tex in human cancers frequently expressed additional cell surface receptors (CD27, CXCR6, LAYN, NKG7, TNFRSF1B, TNFRSF9, TNFRSF18), transcription factors and nuclear proteins (CCND2, RBPJ, ZBED2, ZNF683), as well as chemokines, cytokines, and granzymes (CCL3, CSF1, CXCL13, IFNG, FAM3C, GZMA, GZMB, PRF1). This evidence concerns the gene GZMB and cancer.