In Fig. 2F, we present the estimated slopes for KRT17, which is a well-established therapeutic target in various cancers [179, 180, 181], binding with three type 2 keratins: KRT80 (pattern 1, p-value = 0.006), KRT78 (pattern 2, p-value = 0.03), and KRT6B (pattern 3, p-value = 5.59 × 10−6). The gene discussed is KRT78; the disease is cancer.