Moreover, distinct from other CARMRs, HNRNPA2B1 assumes a pivotal role in N6-methyladenosine methylation to regulate the TGF-β and FOXO pathways, influencing the phenotype of PCa and its response to conventional treatment (Qi et al., 2023; Liyanage et al., 2024). This evidence concerns the gene HNRNPA2B1 and posterior cortical atrophy.