SOAT1 and inflammatory bowel disease: The JAK-STAT pathway regulates immune signaling, involving mediators such as type I interferons, interferon-γ (IFN-γ), and interleukins (IL) 2, 4, 6, 7, 9, 12, 15, 21, 23, and 27, which contribute to the pathogenesis of IBD (Sandborn et al., 2017).