For example, the level of taurine was positively correlated with that of N‐acetylaspartate in the Ccx and Hp of CON mice (R = 0.697 and 0.657, respectively), but the correlation was severely diminished in the AD model group (R = 0.334 and 0.380, respectively), whereas the correlation was significantly recovered in PRE‐treated group (R = 0.669 and 0.625, respectively) (Figures 4C and S16). The gene discussed is HP; the disease is Alzheimer disease.