KCNH2 and Bilateral tonic-clonic seizure: We recorded 2 spontaneous lethal events in Kcnh2(+/7bp−del) rabbits: (1) sudden cardiac death and (2) seizure-mediated sudden death due to generalized tonic-clonic seizures, post-ictal generalized EEG suppression, bradycardia, ECG-T-wave inversion, focal cardiac activity, and asystole/death.