In males, only miR-146a rs2910164-IRAK-1 rs3027898 and IRAK-1 rs3027898-miR-155 rs767649 SNP-SNP interactions contributed to an increased MS risk after multiple comparison adjustments (Bonferroni P < 0.01) (Supplementary Table S9). The gene discussed is IRAK1; the disease is myeloid sarcoma.