Among these interactions, miR-146a rs2910164-rs57095329 and IRAK-1 rs3027898-miR-155 rs767649 were the only ones significantly associated with MS risk in RRMS, even after Bonferroni correction (P = 0.0081 and < 0.0001, respectively). The gene discussed is IRAK1; the disease is myeloid sarcoma.