In contrast, the CGAAT haplotype, which contains the protective A allele of IRAK-1 rs3027898, was 25 times more prevalent in male MS patients than females (CGAAT vs. CGAAA, adjusted OR (95% CI) = 0.04 (0.00–0.73), P = 0.032). The gene discussed is IRAK1; the disease is myeloid sarcoma.