Fig 4E and 4F show that if we group the samples by genotype and challenge, average the lipids abundance values across samples in each group, and compare the wildtype to the LAMP3-KO genotypes in the asthma group, there is a large reduction in phosphatidylglycerols in the LAMP3-KO group, as noted by the authors. Fig 4E also shows the increased abundance of diacylglycerols and decreased amounts of certain sphingolipids and phosphatidylinositols in the wildtype group. Here, LAMP3 is linked to asthma.