Of interest, ANGPTL4 expression also correlated to increased infiltration of Exhausted cytotoxic T cells and decreased infiltration of neutrophils, naïve CD8 + T cells, and B cells, possibly explaining why ANGPTL4 is negatively correlated to inflammation yet has an overall positive correlation with immune infiltration in RCC. This evidence concerns the gene ANGPTL4 and renal cell carcinoma.