SLC25A3 and acute respiratory distress syndrome: In addition, Tyr reduced the expressions of iNOS, COX-2 and PIC and the nuclear translation of NF-kB in LPS-stimulated RAW 264.7 macrophage, resulting in Tyr ameliorating LPS-related ALI, inhibiting NF-κB, reducing the release of PIC and it may be a potential therapeutic agent in inflammatory lung diseases [16].