An unexpected feature of aspergillosis-associated lung injury in hemopexin-deficient animals was an apparent dissociation between the extent of lung injury and number of lung leukocytes — specifically, hemopexin-deficient animals developed higher lung fungal burden than wild-type animals and, independently, also a greater extent of lung injury, but similar number of lung leukocytes (Figures 2 and 5 and Supplemental Figure 2). This evidence concerns the gene HPX and aspergillosis.