RGS1, which prevents TRM tissue egress and lymph node homing, and the TRM-associated chemokine CXCL13 and chemokine receptor CXCR6 were also enriched in CD8+ T cells in patients with CLAD-BOS (Figure 2B) (30, 33–36). This evidence concerns the gene CXCR6 and Buschke-Ollendorff syndrome.