Reflecting our findings from scRNA-Seq, CD8+CD103+ T cells were expanded in patients with BOS compared with NC (mean 118 cells/mm2 versus 12 cells/mm2, P = 0.01) (Figure 7A) as were CD8+CD103+ T cells expressing granzyme B (mean 27 cells/mm2 versus 1 cell/mm2, P = 0.02) (Figure 7B). This evidence concerns the gene GZMB and Buschke-Ollendorff syndrome.