Out of the “hypertension” and “ion transport” related genes, 11 were downregulated (Cntn1, Cacna2d1, Cxcl13, Ttk, Prkg1, Nptx2, Tac3, Serpina6, Mmp10, F10, and Foxf1) and 19 were upregulated (Cyp27b1, Lrrc52, Slc13a4, Slc25a25, Slc38a3, Slc39a4, Tf, Tfrc, Cxcl11, Pde9a, Cyp11a1, Glud1, Cyp2e1, Gstm5, Gsta3, Hmgcs2, Zbtb16, F5, and Tf) commonly in both DK groups (Figure 4, A and B). The gene discussed is PDE9A; the disease is Hypertension.