FBN1 and metabolic dysfunction-associated steatotic liver disease: In this study, male C57BL/6J mice were continuously fed a high‐fat, high‐cholesterol, and high‐fructose (HFHFHC) diet for 12 weeks to induce liver lesions that mimic the clinical characteristics of MASLD.[15] Plasma asprosin levels were initially measured weekly in C57BL/6J mice (Figure 1d).