The results showed that interference with PSIP1 expression partially reversed the promotional and enhancement effects of circRNA‐mTOR on proliferation, colony formation, invasion, metastasis, tumor stemness, and lenvatinib IC50 value in HCC cells and partially reversed the inhibitory effect of circRNA‐mTOR on apoptosis (Figure6A–G; Figure S5A–S5G, Supporting Information). The gene discussed is PSIP1; the disease is hepatocellular carcinoma.