The AKR1B1 aldo‐keto reductase family 1 member B, a protein responsible for catalysing the reduction of aldehydes, shows the highest promiscuity by being a top hit for 36 components, which indicates that some of the extracts can affect pathological processes in diseases such as diabetic retinopathy, cardiovascular disorders, and possibly cancer. This evidence concerns the gene AKR1B1 and diabetic retinopathy.