MALT1 and B-cell chronic lymphocytic leukemia: In addition to ABC-DLBCL, MALT1-dependent activation of the NF-κB transcription factor drives the pathogenesis of multiple other B and T cell malignancies, including subsets of mantle cell lymphoma, adult T cell leukemia, and chronic lymphocytic leukemia with chronic B cell receptor signaling (7, 59–61).