To test the possibility that M1i-124 destabilizes BCL10 and MALT1 within the cell as a consequence of disrupting BCL10-MALT1 interaction, we treated ABC-DLBCL cell lines (TMD8, OCI-Ly3) with M1i-124 for 72 hours and measured the cellular levels of the BCL10 and MALT1 proteins by Western blotting. This evidence concerns the gene CD8B and diffuse large B-cell lymphoma.