SLAMF7 and brucellosis: The association of a type I IFN signature with SLAMF7 and SLAMF8 upregulation in brucellosis and salmonellosis patients together with their high expression in pDCs and the known role of these cells in type I IFN production led us to explore the expression of these 2 surface receptors in purified human pDCs at resting state and after exposure to various stimuli comprising TLR ligands and bacterial components (Figure 3C and Supplemental Figure 2A).