Categorization of brucellosis patients according to their SLAMF7 and SLAMF8 receptor expression (Supplemental Figure 1E) indicated disparity in the global blood transcriptome of these groups, with MAPK11 and VAMP5 as top genes differentially enriched in SLAMFhi patients, and SESN3 and MYBPH in the SLAMFlo group (Supplemental Figure 1F), despite any differences in dominant symptoms and comorbidities (Supplemental Figure 1G). This evidence concerns the gene VAMP5 and brucellosis.