Standard therapyincludes surgery and radiation, but the propensity for distant metastases limits survival [75].Novel approaches, such as targeted therapies like anlotinib, show promise in advanced cases [76].Additionally, high PSMA expressions in ACC tumors suggest that 68Ga-PSMA PET-CT could be a valuable imaging tool for this malignancy[77]. This evidence concerns the gene FOLH1 and adrenal cortex carcinoma.