DPP4 and diabetes mellitus: The present study was conducted with the aimof confirming the hypoglycaemic effect of terminalia arjuna, a natural DPP-4 inhibitor, on patients diagnosed withtype-2 DM, along with an assessment of its efficacy and safety by comparing with a novel synthetic DPP-4 inhibitor Sitagliptin,popularly used oral anti-hyperglycaemic drug.