Meanwhile, they also reported other human regulatory B cells in PD patients and controls, including CD19+ IL-10+, Plasmatic cells IL-10+ (CD19- CD138+ IL-10+), and regulatory B cells (CD19+ CD5+ CD1d+ FOXP3+ IL-10+), but the results indicated no significant difference between PD patients and controls. The gene discussed is CD1D; the disease is Parkinson disease.